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Mersal
Samantha Ruth Prabhu’s 2017 film Mersal is her highest-grossing movie. This film with Thalapathy Vijay collected 257 crores. The movie’s budget was 120 crores.

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Rangasthalam
Samantha’s 2018 film Rangasthalam grossed 217 crores. Made on an 80 crore budget, it starred Ram Charan.
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Theri
Samantha Ruth Prabhu’s film Theri with Thalapathy Vijay came out in 2016. Made on a budget of 75 crores, this film did business of 153 crores.
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Janatha Garage
Made on a budget of 60 crores, Samantha’s film Janatha Garage did business of 135 crores at the box office. Jr. NTR was in the lead role.
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Attarintiki Daredi
Samantha’s film Attarintiki Daredi was released in 2013. Made on a 55 crore budget, it grossed 134 crores. Pawan Kalyan was the lead actor in the film.
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Kaththi
Samantha’s 2014 film Kaththi was made on a budget of 65 crores. This movie with Thalapathy Vijay collected 126.8 crores at the box office.
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24
In Samantha’s film 24, her lead hero was Suriya. Made on a 75 crore budget, this film did business of 108 crores. The movie was released in 2016.
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Eega
Samantha Ruth Prabhu’s 2012 film Eega had a budget of 45 crores. This movie with Nani earned 102 crores.
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Dookudu
In Samantha’s 2011 film Dookudu, Mahesh Babu was in the lead role. Made on a 35 crore budget, this movie did business of 101 crores.
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Seethamma Vakitlo Sirimalle Chettu
In Samantha’s 2013 film Seethamma Vakitlo Sirimalle Chettu, Venkatesh Daggubati was the lead. Made on a 45 crore budget, it earned 92 crores.