India and China could see 6.5 million gastric cancer cases combined
The study highlights that India and China together could account for approximately 6.5 million new gastric cancer cases in the coming decades. This projection positions Asia as the global hotspot for the disease. The rise is largely driven by factors such as rapid population growth, increasing life expectancy, and a continued prevalence of key risk factors—many of which are still not adequately addressed through public health measures. These include poor sanitation, limited access to healthcare, and dietary habits that may increase stomach cancer risk.
Helicobacter pylori infection causes most gastric cancer cases in India
One of the most important takeaways from the study is that Helicobacter pylori (H. pylori) infection is the leading cause of future gastric cancer cases—accounting for about 76% of them. This bacterium infects the lining of the stomach and can remain undetected for years. Over time, it causes inflammation that can lead to ulcers and eventually cancer. In India, where access to preventive screening is limited and awareness is low, H. pylori often goes untreated, significantly raising the risk of long-term health complications. The study urges stronger surveillance and early intervention programmes to tackle this hidden epidemic.
Gastric cancer is rising in India faster than in many regions
Currently, gastric cancer is the fifth most common cause of cancer-related death worldwide, but its burden is not evenly distributed. While some regions, like Sub-Saharan Africa, report relatively low incidence rates today, the study warns of a six-fold increase in cases in those areas over time. In contrast, India’s numbers are expected to rise more sharply and sooner due to existing health inequalities, limited diagnostic infrastructure, and lack of widespread awareness about early symptoms. This puts millions of Indians at a heightened and preventable risk.
Early detection could prevent most gastric cancer cases
The research points to a clear solution: early screening and treatment of H. pylori can dramatically reduce future cases of gastric cancer—by as much as 75%. In countries like India, where healthcare resources may be stretched, focusing on population-wide, low-cost screening initiatives could be a game-changer. Treating H. pylori with antibiotics and simple follow-up care could save countless lives and significantly ease the burden on the healthcare system. These preventive steps are not only scientifically sound but also financially viable.
Younger populations in India face rising gastric cancer risk
Perhaps the most alarming finding from the study is that gastric cancer is increasingly affecting younger individuals, especially those born after 2008. This is a major shift from previous decades when the disease primarily affected older adults.
Combined with India’s ageing population, this trend could create a dual burden of both young and elderly patients requiring long-term cancer care. Without timely intervention, India risks reversing years of public health progress in cancer control.